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Carboxylic acids and their derivatives are characterized by the carboxyl group. They include esters, acid chlorides, anhydrides, amides, and nitriles. Carboxylic acids and their derivatives undergo nucleophilic addition-elimination reactions at the carbonyl carbon. Acid chlorides are the most reactive as they have chloride as a good leaving group. Esters, acids, and amides react through protonation to generate alcohol, water, or amine leaving groups. Reactivity decreases down this series. Derivatives can be

Author

Amany

Language

EN