Opening book details…
Can I read In Vitro Hypoxia Induces Expression of the NR2C Subunit of the NMDA Receptor in Rat Cortex and Hippocampus on EtoBox?
In Vitro Hypoxia Induces Expression of the NR2C Subunit of the NMDA Receptor in Rat Cortex and Hippocampus by Jose L. Perez‐Velazquez; Liang Zhang is a Neuroscience article available to read on EtoBox.
What is In Vitro Hypoxia Induces Expression of the NR2C Subunit of the NMDA Receptor in Rat Cortex and Hippocampus about?
Abstract: In mammalian brain, ischemic injury could be mediated by delayed glutamate neurotoxicity. We have studied the possibility of altered genetic expression of quiescent NMDA receptor subunits in an in vitro model of hypoxia‐hypoglycemia, using the reverse transcription‐polymerase chain reaction technique. It was found that mRNA corresponding to the NR2C subunit was present 1 h after a brief hypoxic‐hypoglycemic episode in adult rat hippocampus and cortex but absent in control tissue. These findings indicate that the phenotypic characteristics of certain brain cells after an ischemic insult are altered by the expression of genes that are quiescent in those cells under normal physiological conditions.
Who reads In Vitro Hypoxia Induces Expression of the NR2C Subunit of the NMDA Receptor in Rat Cortex and Hippocampus?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Jose L. Perez‐Velazquez; Liang Zhang
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0022-3042)
- Published
- 1994
- Language
- EN
- Field
- Neuroscience (Life Sciences)