Can I read Quantitative estimation of mouse mammary tumor virus (MTV) antigens by radioimmunoassay on EtoBox?

Quantitative estimation of mouse mammary tumor virus (MTV) antigens by radioimmunoassay by A. A. Verstraeten; R. Van Nie; H. G. Kwa; Ph. C. Hageman is a Medicine article available to read on EtoBox.

What is Quantitative estimation of mouse mammary tumor virus (MTV) antigens by radioimmunoassay about?

## Abstract A radioimmunoassay for the antigens of the mouse mammary tumour virus has been developed. ^125^Iodine‐labelling of intact virus [derived from mammary tumours of (C3H × 020) F1 mice] followed by ether extraction and separation of the ether and water layers resulted in a separation of the labelled material into two main groups of antigenic components. The intact labelled material from each group was separated from viral debris and other possible contaminants by affinity chromatography. The antigens of the ether phase were proved to belong mainly to the viral nucleoid whereas the water phase contained mainly envelope antigens. No type‐specific antigens could be demonstrated in either of the phases. Radioimmunological assessment of plasma revealed that in the plasma of MTV‐S‐ and MTV‐P‐positive animals viral antigens were only measurable when palpable mammary tumours were present, whereas in MTV‐L‐positive tumour‐bearing animals some negative samples were found. In milk of individual nontumour‐bearing mice a close correlation was found between the expression of viral antigens and the generally accepted presence of virus in the strain of mice. In milk, viral antigen levels t

Who reads Quantitative estimation of mouse mammary tumor virus (MTV) antigens by radioimmunoassay?

Author

A. A. Verstraeten; R. Van Nie; H. G. Kwa; Ph. C. Hageman

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

1975

Language

EN

Field

Medicine (Health Sciences)