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Neurally Adjusted Ventilatory Assist in Neonates with Congenital Diaphragmatic Hernia by Yonatan Kurland; Kamal Gurung; Eugenia K. Pallotto; Winston Manimtim; Keith Feldman; Vincent S. Staggs; William Truog is a Medicine article available to read on EtoBox.

What is Neurally Adjusted Ventilatory Assist in Neonates with Congenital Diaphragmatic Hernia about?

## Objective: To measure short-term outcomes of neonates with congenital diaphragmatic hernia (cdh) while on neurally adjusted ventilator assist (nava), and to measure the impact of a congenitally abnormal diaphragm on nava ventilator indices. ## Study design: First, we conducted a retrospective-cohort analysis of 16 neonates with cdh placed on nava over a treatment period of 72 h. second, we performed a case-control study comparing nava level and edi between neonates with cdh and those without cdh. ## Results: Compared to pre-nava, there were clinically meaningful improvements in pip (p < 0.003), respiratory severity score (p < 0.001), map (p < 0.001), morphine (p = 0.004), and midazolam use (p = 0.037). compared to a 1:2 matched group without cdh, there was no meaningful difference in nava level (p = 0.286), edi-peak (p = 0.315), or edi-min (p = 0.266). ## Conclusions: The potential benefits of nava extend to neonates with cdh. there is minimal compensatory change in edis, and higher/lower ventilator settings compared to neonates without cdh.

Who reads Neurally Adjusted Ventilatory Assist in Neonates with Congenital Diaphragmatic Hernia?

Author

Yonatan Kurland; Kamal Gurung; Eugenia K. Pallotto; Winston Manimtim; Keith Feldman; Vincent S. Staggs; William Truog

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)