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Toxic effects of lead exposure on bioaccumulation, oxidative stress, neurotoxicity, and immune responses in fish: A review by Ju-Wook Lee; Hoon Choi; Un-Ki Hwang; Ju-Chan Kang; Yue Jai Kang; Kwang Il Kim; Jun-Hwan Kim is a Environmental Science article available to read on EtoBox.

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Lead (Pb) is a highly toxic metal in aquatic environments. Fish are at the top of the food chain in most aquatic environments, and are the most susceptible to the toxic effects of Pb exposure. In addition, fish are one of the most abundant vertebrates, and they can directly affect humans through food intake; therefore, fish can be used to assess the extent of environmental pollution in an aquatic environment. Pb-induced toxicity in fish exposed to toxicants is primarily induced by bioaccumulation in specific tissues, and the accumulation mechanisms vary depending on water habitat (freshwater or seawater) and pathway (waterborne or dietary exposure). Pb accumulation in fish tissues causes oxidative stress due to excessive ROS production. Oxidative stress by Pb exposure induces synaptic damage and neurotransmitter malfunction in fish as neurotoxicity. Moreover, Pb exposure influences immune responses in fish as an immune-toxicant. Therefore, the purpose of this review was to examine the various toxic effects of Pb exposure, including bioaccumulation, oxidative stress, neurotoxicity, and immune responses, and to identify indicators to evaluate the extent of Pb toxicity by based on the

Who reads Toxic effects of lead exposure on bioaccumulation, oxidative stress, neurotoxicity, and immune responses in fish: A review?

Author

Ju-Wook Lee; Hoon Choi; Un-Ki Hwang; Ju-Chan Kang; Yue Jai Kang; Kwang Il Kim; Jun-Hwan Kim

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1382-6689)

Published

2019

Language

EN

Field

Environmental Science (Physical Sciences)