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The study investigates the anti-hyperglycemic effects of Vatairea macrocarpa stem-bark ethanolic extract (VmE) in diabetic rats, focusing on its impact on insulin signaling pathways in peripheral tissues. Results indicate that VmE treatment enhances insulin receptor content and AKT phosphorylation in the liver, adipose tissue, and skeletal muscle, while reducing phosphoenolpyruvate carboxykinase levels, suggesting a mechanism for improved glucose uptake and glycogen synthesis. These findings support the pot

Author

Agnes Contar

Language

EN