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The study investigates the role of Escherichia coli in benign prostate hyperplasia (BPH) and its association with inflammation and DNA damage in prostate epithelial cells. It found that E. coli, a common bacterium in BPH-associated microbiota, can activate NF-κB signaling and induce DNA damage, contributing to the inflammatory environment in BPH tissues. The research highlights the complex microbial composition in BPH and its potential implications for prostate health.

Author
sanghamitra satpathi
Language
EN

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