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A high likelihood of increase in end-stage renal disease among the Japanese HIV-infected population by Ando, Minoru; Ando, Yoko is a Medicine article available to read on EtoBox.

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Abstract Kidneys are affected by human immunodeficiency virus (HIV) infection and its associated therapies. Antiretroviral therapy (ART) has markedly reduced acquired immune deficiency syndrome–related deaths and opportunistic infectious diseases among HIV-infected patients. This contributed to their prolonged survival; however, the improvement in survival has been accompanied by an increase in the incidence of non-infectious chronic complications, including hypertension, metabolic diseases, and chronic kidney disease (CKD). Recent studies showed that estimated prevalence of any CKD and end-stage renal disease (ESRD) among HIV-infected patients is approximately 20% and 0.5%, respectively, in Japan. Both a rapid decrease in renal function and a high positive rate of albuminuria and proteinuria are clinical characteristics of HIV-infected patients. Moreover, considering higher complication rates of hypertension and diabetes compared with non-HIV-infected individuals of the similar aging, HIV-infected patients who develop CKD and ESRD are very likely to increase. Furthermore, as the survival rate is favorable after the initiation of dialysis, the cumulative number of ESRD patients is

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Author

Ando, Minoru; Ando, Yoko

Publisher

Springer (Biomed Central Ltd.); London: BioMed Central, 2015-; Springer Science and Business Media LLC (ISSN 2059-1381)

Published

2019

Language

EN

Field

Medicine (Health Sciences)