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C38. AUTOIMMUNE, DRUG RELATED, AND TRANSPLANT - Single Center Experience of ROSE+BALF+TBLB+NGS in Diagnose of Pneumocystis Pneumonia in Lung Transplant Recipients by Zhang, J. is a scholarly article available to read on EtoBox.

What is C38. AUTOIMMUNE, DRUG RELATED, AND TRANSPLANT - Single Center Experience of ROSE+BALF+TBLB+NGS in Diagnose of Pneumocystis Pneumonia in Lung Transplant Recipients about?

Background: Infection and acute rejection are difficult to identify, but the treatment is completely different in lung transplant recipients. Unfortunately, the routine pathogenic culture is difficult to give any notice, especially for Pneumocystis pneumonia (PCP). Objectives: Establish a rapid diagnosis method for PCP including rapid on site evaluation (ROSE) + bronchoalveolar lavage (BALF) + transbronchial lung biopsy (TBLB) + next generation sequencing (NGS) is demanded. Methods: We performed a bedside rapid diagnose including ROSE +BALF + TBLB+NGS for 35 lung transplant recipients with diffuse effusion between December 2017 and October 2018. The routine pathogen/pathological examination and NGS were performed. Results: 35 patients were performed with ROSE + BALF + TBLB + NGS. 6 cases of PCP were diagnosed , including 3 cases of PCP + CMV, 2 cases of PCP + EBV, 1 case of PCP + Aspergillus, 1 case of PCP + multi-drug resistant Klebsiella pneumoniae and Pseudomonas aeruginosa, 1 case of Acute cellular rejection(ACR). The 6 patients were 28-63 years old, the primary disease is 3 Idiopathic pulmonary fibrosis , 1 COPD , 1 branch expansion , 1 Occlusive bronchiolitis after hematopoie

Author

Zhang, J.

Publisher

American Thoracic Society

Published

2019

Language

EN