Can I read Cold air exposure at − 15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction on EtoBox?

Cold air exposure at − 15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction by Linda M. Eklund; Åsa Sköndal; Ellen Tufvesson; Rita Sjöström; Lars Söderström; Helen G. Hanstock; Thomas Sandström; Nikolai Stenfors is a Medicine article available to read on EtoBox.

What is Cold air exposure at − 15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction about?

## Abstract ## Purpose Exposure to cold air may harm the airways. It is unclear to what extent heavy exercise adds to the cold-induced effects on peripheral airways, airway epithelium, and systemic immunity among healthy individuals. We investigated acute effects of heavy exercise in sub-zero temperatures on the healthy airways. ## Methods Twenty-nine healthy individuals underwent whole body exposures to cold air in an environmental chamber at − 15 °C for 50 min on two occasions; a 35-min exercise protocol consisting of a 5-min warm-up followed by 2 × 15 min of running at 85% of VO~2~max vs. 50 min at rest. Lung function was measured by impulse oscillometry (IOS) and spirometry before and immediately after exposures. CC16 in plasma and urine, and cytokines in plasma were measured before and 60 min after exposures. Symptoms were surveyed pre-, during and post-trials. ## Results FEV~1~ decreased after rest (− 0.10 ± 0.03 L, p < 0.001) and after exercise (− 0.06 ± 0.02 L, p = 0.012), with no difference between trials. Exercise in − 15 °C induced greater increases in lung reactance (X5; p = 0.023), plasma CC16 (p < 0.001) as well as plasma IL-8 (p < 0.001), compared to rest. Exercise i

Who reads Cold air exposure at − 15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction?

Author

Linda M. Eklund; Åsa Sköndal; Ellen Tufvesson; Rita Sjöström; Lars Söderström; Helen G. Hanstock; Thomas Sandström; Nikolai Stenfors

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)