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Time Constant = Compliance x Resistance Time constant is the time required for the lung to inflate or deflate by 63% of the maximal change in volume in response to a step change in pressure or flow. A higher time constant means it takes longer for the lung to respond to changes in pressure or flow. In acute RDS, compliance is low so time constant is high. In meconium aspiration syndrome, compliance is often normal or high so time constant is low. The time constant is important throughout mechanical vent

Author

hari

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EN