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Differences in Antimicrobial Activity of Four Commercial 0.12% Chlorhexidine Mouthrinse Formulations: an in Vitro Contact Test and Salivary Bacterial Counts Study by David Herrera; Silvia Roldán; Isabel Santacruz; Sagrario Santos; Mireia Masdevall; Mariano Sanz is a Dentistry article available to read on EtoBox.
What is Differences in Antimicrobial Activity of Four Commercial 0.12% Chlorhexidine Mouthrinse Formulations: an in Vitro Contact Test and Salivary Bacterial Counts Study about?
## Abstract **Aim:** To evaluate the in vitro and in vivo antimicrobial activity of four commercial 0.12% chlorhexidine mouthrinses. **Material and methods:** The in vitro antimicrobial activity test consisted in a modified contact test where 20 selected bacterial species were tested during 1 min with each test product. After the contact, the inoculum was cultured, and the results were expressed in terms of survival/resistance and the percentage of survival as compared to a saline control. The in vivo test consisted of a double‐blind, randomized, crossover salivary bacterial counts study. 10 volunteers rinsed during 1 min with each tested product. Saliva samples were obtained before rinsing, and after 5 min, and 1, 3, 5 and 7 h. These samples were cultured both aerobically and anaerobically. Percentages of survival, in regard to baseline, were calculated for each time point. Comparisons among products were tested using anova and selected paired __t__‐test. **Results:** The in vitro contact test showed no survival in any tested species with CHX+CPC, while three species (__Lactobacillus casei, Streptococcus mitis__ and __Peptostreptococcus micros__) were resistant to the other thr
Who reads Differences in Antimicrobial Activity of Four Commercial 0.12% Chlorhexidine Mouthrinse Formulations: an in Vitro Contact Test and Salivary Bacterial Counts Study?
It is typically read by researchers, students, and practitioners in Dentistry.
- Author
- David Herrera; Silvia Roldán; Isabel Santacruz; Sagrario Santos; Mireia Masdevall; Mariano Sanz
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0303-6979)
- Published
- 2003
- Language
- EN
- Field
- Dentistry (Health Sciences)