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DDX4 Transcript Deletion Impacts Zebrafish Oogenesis by lucasmaiamed02 is a document available to read on EtoBox.
The study investigates the role of the ovary-specific transcript ddx4-L in zebrafish, revealing that its deletion leads to enlarged ovaries and reduced egg fertilization rates. RNA-seq analysis indicates significant downregulation of meiosis-related genes and derepression of DNA transposons in ddx4-L mutant ovaries, suggesting a link to oogenesis dysfunction. These findings enhance understanding of sex-specific alternative splicing and its biological implications in zebrafish reproduction.
- Author
- lucasmaiamed02
- Language
- EN