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The document discusses drug-induced liver toxicity, which is a significant cause of liver injury and accounts for many cases of acute liver failure. It outlines the pathogenesis, risk factors, and various mechanisms of liver damage caused by drugs, including direct cytotoxicity, interference with bilirubin transport, cholestatic injury, fatty liver, and chronic hepatitis. Over 900 drugs have been implicated, with factors such as genetic predisposition and concurrent drug use influencing the risk of hepatoto

Author

broniagyayaw

Language

EN