About this document
Fphar 13 835979 by Jorge Murguia Cervantes is a document available to read on EtoBox.
This research investigates the effects of arachidonoylcyclopropylamide (ACPA), a selective CB1R agonist, on bleomycin-induced pulmonary fibrosis. ACPA treatment improved survival rates and reduced fibrosis by inhibiting TGF-β-Smad2/3 signaling in lung fibroblasts, suggesting a potential therapeutic approach for pulmonary fibrosis. The findings highlight the role of CB1R in modulating fibroblast activation and extracellular matrix production in the context of fibrosis.
- Author
- Jorge Murguia Cervantes
- Language
- EN