Can I read R-cadherin Expression in the Developing and Adult Zebrafish Visual System on EtoBox?

R-cadherin Expression in the Developing and Adult Zebrafish Visual System by Liu, Q.; Sanborn, K.L.; Cobb, N.; Raymond, P.A.; Marrs, J.A. is a Neuroscience article available to read on EtoBox.

What is R-cadherin Expression in the Developing and Adult Zebrafish Visual System about?

Cell adhesion molecules in the cadherin family have been implicated in histogenesis and maintenance of cellular structure and function in several organs. Zebrafish have emerged as an important new developmental model, but only three zebrafish cadherin molecules have been identified to date (N-cadherin, paraxial protocadherin, and VN-cadherin). We began a systematic study to identify other zebrafish cadherins by screening zebrafish cDNA libraries using an antibody raised to the cytoplasmic domain of mouse E-cadherin. Here, we report a partial cDNA with extensive sequence homology to R-cadherin. Spatial and temporal expression of this putative zebrafish R-cadherin was examined in embryos and adults by Northern analysis, RNase protection, and in situ hybridization. R-cadherin message increased during embryogenesis up to 80 hours postfertilization (hpf) and persisted in adults. In the embryonic brain, R-cadherin was first expressed in groups of cells in the diencephalon and pretectum. In adult zebrafish brain, R-cadherin continued to be expressed in several specific regions including primary visual targets. In the retina, R-cadherin was first detected at about 33 hours postfertilizatio

Who reads R-cadherin Expression in the Developing and Adult Zebrafish Visual System?

Author

Liu, Q.; Sanborn, K.L.; Cobb, N.; Raymond, P.A.; Marrs, J.A.

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0021-9967)

Published

1999

Language

EN

Field

Neuroscience (Life Sciences)