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What is Synthetic Peptide Purification Method about?
This article presents a new methodology for the purification of synthetic peptides and simultaneous counterion exchange using solid-phase extraction chromatography. The developed methods allow for the efficient exchange of trifluoroacetate counterions to hydrochloride or acetate, yielding peptides with high purity and low trifluoroacetate content. The techniques are cost-effective, rapid, and can be routinely implemented, contributing significantly to peptide-based therapeutic development.
- Author
- LKA Garci
- Language
- EN