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What is TLR4 Promotes Colorectal Cancer Progression via Activating the NF-κB Signaling Pathway about?

This research article investigates the role of TLR4 in promoting colorectal cancer (CRC) progression through the activation of the NF-κB signaling pathway. The study finds that TLR4 is upregulated in CRC cell lines, and its overexpression enhances cell proliferation, migration, and invasion, while knockdown of TLR4 shows opposite effects. These findings suggest that TLR4 could serve as a potential therapeutic target for CRC.

Author

mccrj.urfpublishers

Language

EN