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This study evaluates three experimental extracellular matrix (ECM) meshes—human acellular dermis (HAD), porcine acellular dermis (PAD), and porcine small intestinal submucosa (SIS)—for soft tissue remodeling through integrated in vitro and in vivo analyses. Results indicate that HAD exhibited superior structural stability and promoted favorable macrophage polarization, while SIS degraded rapidly but caused significant immune reactions. The findings establish a multi-dimensional assessment framework to guide

Author

SUBHADIP MANIK

Language

EN