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Can I read Evidence for Multiple Tumor Suppressor Genes on Chromosome Arm 8P in Supraglottic Laryngeal Cancer on EtoBox?
Evidence for Multiple Tumor Suppressor Genes on Chromosome Arm 8P in Supraglottic Laryngeal Cancer by John B. Sunwoo; Matthew S. Holt; Diane M. Radford; Courtney Deeker; Steven B. Scholnick is a Medicine article available to read on EtoBox.
What is Evidence for Multiple Tumor Suppressor Genes on Chromosome Arm 8P in Supraglottic Laryngeal Cancer about?
Loss of heterozygosity studies of a variety of human tumors suggest that there are several tumor suppressor genes on chromosome arm 8p. To localize these genes more precisely. we utilized polymerase chain reaction amplification of microsatellie repeat polymorphism and examined the allelic IOU patterns of I7 marker loci on 8p in a population of 59 suptaglottic laryngeal squamous cell carcinomas. Twenty-three of these tumors (39%) had an allelic loss at one or more of the markers examined. The allelic loss patterns o f these tumors support the presence of at least three different tumor suppressor genes on 8p: one in 8p23, one in 8p22-23, and another in 8p2I.
Who reads Evidence for Multiple Tumor Suppressor Genes on Chromosome Arm 8P in Supraglottic Laryngeal Cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- John B. Sunwoo; Matthew S. Holt; Diane M. Radford; Courtney Deeker; Steven B. Scholnick
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Liss Inc; Wiley (ISSN 1045-2257)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Life Sciences)