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Can I read In vitro antitumor activities of 2,6-di-[2-(Heteroaryl)vinyl]pyridines and pyridiniums on EtoBox?
In vitro antitumor activities of 2,6-di-[2-(Heteroaryl)vinyl]pyridines and pyridiniums by Vincenza Barresi; Daniele F Condorelli; Cosimo G Fortuna; Giuseppe Musumarra; Salvatore Scirè is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is In vitro antitumor activities of 2,6-di-[2-(Heteroaryl)vinyl]pyridines and pyridiniums about?
The in vitro antitumor activities of 2,6-di-[2-(heteroaryl)vinyl]pyridines versus the standard National Cancer Institute 60 cell lines panel and of 2,6-di-[2-(heteroaryl)vinyl] pyridinium cations versus MCF7 (human mammary carcinoma) and LNCap (prostate carcinoma) cell lines are reported. Antiproliferative effects in both series are particularly evident for MCF7 mammary adenocarcinoma cells. Multivariate analysis of DNA microarray data for responsive tumor cell lines suggest a mechanistic pathway involving polyamine biosynthesis and prolactin signal transduction.
Who reads In vitro antitumor activities of 2,6-di-[2-(Heteroaryl)vinyl]pyridines and pyridiniums?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Vincenza Barresi; Daniele F Condorelli; Cosimo G Fortuna; Giuseppe Musumarra; Salvatore Scirè
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0968-0896)
- Published
- 2002
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)