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Glucocorticoids: Impact on Muscle and Bone by willy christian is a document available to read on EtoBox.

The document discusses how glucocorticoids negatively impact muscle and bone through various pathways. It causes muscle wasting and directly induces factors in osteocytes that inhibit bone formation. Glucocorticoids also upregulate osteoclastic bone resorption by suppressing osteoprotegerin and inducing proteolytic enzymes in osteoclasts. Therapeutic interventions can prevent bone loss by targeting osteoblast and osteoclast anabolism or catabolism.

Author

willy christian

Language

EN