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Can I read Regulation of B lymphocyte activation by the Fc portion of immunoglobulin on EtoBox?
Regulation of B lymphocyte activation by the Fc portion of immunoglobulin by Edward L. Morgan; William O. Weigle is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Regulation of B lymphocyte activation by the Fc portion of immunoglobulin about?
## Abstract Murine splenic B lymphocytes are induced to proliferate and undergo polyclonal activation in the presence of Fc fragments, AHGG, antigen‐antibody complexes, and CH~3~ fragments derived from plasmin digestion of human Ig. The unifying feature of the polyclonal antibody response induced by these agents is that in all cases a portion of the constant region of the Ig molecule (ie, Fc region) is present. Fragments of Ig lacking the Fc piece, such as Fab and F(ab′)~2~ were found not to be stimulatory. In addition, a model is proposed to account for the regulatory effects of antigen‐antibody complexes on an ongoing humoral immune response.
Who reads Regulation of B lymphocyte activation by the Fc portion of immunoglobulin?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Edward L. Morgan; William O. Weigle
- Publisher
- Wiley (John Wiley & Sons); Alan R. Liss, Inc.; Wiley (ISSN 0091-7419)
- Published
- 1980
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)