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Prediction of kLa in yeast broths by Francisco J. Montes; Jacinto Catalán; Miguel A. Galán is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Prediction of kLa in yeast broths about?

Oxygen transfer rate, can play an important role in the scale-up and economy of many microbial processes and values of the volumetric oxygen transfer coefficient (k L a) for specific fermentation culture media need to be evaluated and correlated to obtain the appropriate design tools. The purpose of this work was to determinate the values of k L a in yeast broths (Trigonopsis 6ariabilis) in a mechanically-stirred, sparger-aerated and baffled reactor, the most common fermenter type, over a wide range of superficial air velocities impeller rotational speeds and geometric parameters. Three different mixing vessels (2, 5 and 15 litres) were used in order to consider the effect of the fermenter scale-up on k L a. Once k L a data are obtained, several empirical and theoretical correlations were used to fit the experimental data. A new correlation is proposed based on the power input per unit volume of liquid (P/V) and the superficial gas velocity (U sg ). The correlation improves the prediction of k L a values in culture media with respect to other generic correlations, mainly because early correlations were developed for strong coalescent and non-coalescent fluids, whereas the medium us

Who reads Prediction of kLa in yeast broths?

Author

Francisco J. Montes; Jacinto Catalán; Miguel A. Galán

Publisher

Elsevier Science; Elsevier ; Elsevier Applied Science; Elsevier BV (ISSN 1873-3298)

Published

1999

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)