Can I read Effects of Age, Gender and Metabolic Factors on Endothelium-dependent Vasodilation: a Population-based Study on EtoBox?

Effects of Age, Gender and Metabolic Factors on Endothelium-dependent Vasodilation: a Population-based Study by M. Sarabi; J. Millgård; L. Lind is a Medicine article available to read on EtoBox.

What is Effects of Age, Gender and Metabolic Factors on Endothelium-dependent Vasodilation: a Population-based Study about?

Abstract. Sarabi M, Millgård J, Lind L (University Hospital, Uppsala, Sweden). Effects of age, gender and metabolic factors on endothelium‐dependent vasodilation: a population‐based study. __J Intern Med__ 1999; 246: 265–274. Objectives. A progressive decline in endothelium‐dependent vasodilation (EDV) in the human forearm with age has previously been reported. The aim of this study was to evaluate the interplay between age, gender and metabolic factors on EDV in healthy subjects in a population‐based study. Setting. Tertiary university hospital. Subjects and design. Thirty‐six healthy men and 30 women, aged 20–69 years, underwent measurements of forearm blood flow (FBF) at rest and during local infusions of 2 and 4 μg min^–1^ of metacholine (evaluating EDV) and 5 and 10 μg min^–1^ of sodium nitroprusside (evaluating endothelium‐independent vasodilation, EIDV) and during reactive hyperaemia by venous occlusion plethysmography. Results. Age was inversely related to EDV (__r__ = – 0.41, __P__ < 0.05 in men; __r__ = – 0.61, __P__ < 0.01 in women) and maximal FBF during reactive hyperaemia in both men and women. EIDV was significantly related to age in an inverse way in women only. EDV

Who reads Effects of Age, Gender and Metabolic Factors on Endothelium-dependent Vasodilation: a Population-based Study?

Author

M. Sarabi; J. Millgård; L. Lind

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0954-6820)

Published

1999

Language

EN

Field

Medicine (Health Sciences)