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Mechanism and Uses of Bisphosphonates by huma is a document available to read on EtoBox.
Bisphosphonates inhibit bone resorption by suppressing osteoclasts. They bind strongly to bone mineral and accumulate over time. Oral bisphosphonates are used to treat osteoporosis while intravenous bisphosphonates are used in patients with cancer and bone metastases. Bisphosphonate-related osteonecrosis of the jaw (BONJ) occurs due to a complex interplay of factors including local trauma, increased bone repair demands, and reduced vascularity in patients taking bisphosphonates. Treatment focuses on pain co
- Author
- huma
- Language
- EN