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This study evaluates the measurement of hydroxyproline in collagen using liquid chromatography-mass spectrometry (LC-MS) compared to colorimetric and high-performance liquid chromatography (HPLC) methods. The results indicate that LC-MS offers improved sensitivity and simplicity for diagnosing collagen metabolism disorders, which are linked to various diseases such as fibrosis and liver cancer. The study highlights the effectiveness of LC-MS in accurately quantifying hydroxyproline concentrations in lung an

Author

Pedro Miguel Cueva Martínez

Language

EN