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Physical Activity Modifies the Relation Between Gestational Perfluorooctanoic Acid Exposure and Adolescent Cardiometabolic Risk by Joseph M. Braun; George D. Papandonatos; Nan Li; Clara G. Sears; Jessie P. Buckley; Kim M. Cecil; Aimin Chen; Charles B. Eaton; Heidi J. Kalkwarf; Karl T. Kelsey; Bruce P. Lanphear; Kimberly Yolton is a Environmental Science article available to read on EtoBox.
What is Physical Activity Modifies the Relation Between Gestational Perfluorooctanoic Acid Exposure and Adolescent Cardiometabolic Risk about?
## Objective: Exposure to per- and polyfluoroalkyl substances (pfas) - endocrine disrupting chemicals - may increase cardiometabolic risk. we evaluated whether adolescent lifestyle factors modified associations between gestational pfas exposure and cardiometabolic risk using a prospective cohort study. ## Methods: In 166 mother-child pairs (home study), we measured concentrations of four pfas in maternal serum collected during pregnancy. when children were age 12 years, we calculated cardiometabolic risk scores from visceral adiposity area, blood pressure, and fasting serum biomarkers. we assessed adolescent physical activity and healthy eating index scores using the physical activity questionnaire for older children (paq-c), actigraphy, and 24-h diet recalls. using multivariable linear regression and weighted quantile sum regression, we examined whether physical activity or diet modified covariate-adjusted associations of pfas and their mixture with cardiometabolic risk scores. ## Results: Physical activity modified associations between perfluorooctanoic acid (pfoa) and cardiometabolic risk scores. each doubling of pfoa was associated with worse cardiometabolic risk scores among c
Who reads Physical Activity Modifies the Relation Between Gestational Perfluorooctanoic Acid Exposure and Adolescent Cardiometabolic Risk?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- Joseph M. Braun; George D. Papandonatos; Nan Li; Clara G. Sears; Jessie P. Buckley; Kim M. Cecil; Aimin Chen; Charles B. Eaton; Heidi J. Kalkwarf; Karl T. Kelsey; Bruce P. Lanphear; Kimberly Yolton
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Environmental Science (Physical Sciences)