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Prevention of non-ventilator-associated hospital-acquired pneumonia in Switzerland: a type 2 hybrid effectiveness–implementation trial by Aline Wolfensberger; Lauren Clack; Stefanie von Felten; Mirjam Faes Hesse; Dirk Saleschus; Marie-Theres Meier; Katharina Kusejko; Roger Kouyos; Leonhard Held; Hugo Sax is a Medicine article available to read on EtoBox.

What is Prevention of non-ventilator-associated hospital-acquired pneumonia in Switzerland: a type 2 hybrid effectiveness–implementation trial about?

Background Non-ventilator-associated hospital-acquired pneumonia (nvHAP) is a frequent, but under-researched infection. We aimed to simultaneously test an nvHAP prevention intervention and a multifaceted implementation strategy. Methods In this single-centre, type 2 hybrid effectiveness–implementation study, all patients of nine surgical and medical departments at the University Hospital Zurich, Switzerland, were included and surveyed over three study periods: baseline (14–33 months, depending on department), implementation (2 months), and intervention (3–22 months, depending on department). The five-measure nvHAP prevention bundle consisted of oral care, dysphagia screening and management, mobilisation, discontinuation of non-indicated proton-pump inhibitors, and respiratory therapy. The implementation strategy comprised department-level implementation teams who conducted and locally adapted the core strategies of education, training, and changing infrastructure. Intervention effectiveness on the primary outcome measure of nvHAP incidence rate was quantified using a generalised estimating equation method in a Poisson regression model, with hospital departments as clusters. Impleme

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Author

Aline Wolfensberger; Lauren Clack; Stefanie von Felten; Mirjam Faes Hesse; Dirk Saleschus; Marie-Theres Meier; Katharina Kusejko; Roger Kouyos; Leonhard Held; Hugo Sax

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)