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Can I read Expression in lung tumors and genetic mapping of the novel murine protein kinase Cη on EtoBox?
Expression in lung tumors and genetic mapping of the novel murine protein kinase Cη by Federico Canzian; Manuela Gariboldi; Giacomo Manenti; Laura De Gregorio; Shin‐Ichi Osada; Shigeo Ohno; Tommaso A. Dragani; Marco A. Pierotti is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Expression in lung tumors and genetic mapping of the novel murine protein kinase Cη about?
## Abstract Protein kinase Cη (nPKCη) is a member of the protein kinase C family with a unique tissue distribution in skin and lung. We analyzed nPKCη expression in normal murine lung and in 36 lung tumors induced by urethane in AC3 F1 and F2 mice. The nPKCη‐related transcript was present at fivefold to tenfold lower levels in tumors than in normal lung controls. We mapped two distinct loci for nPKCη on murine chromosome 12, using linkage analysis in an interspecific test cross. The results indicate that the mouse Pkcn‐rs1 and Pkcn‐rs2 loci were about 30 cM from the centromere and about 2 cM from each other. © 1994 Wiley‐Liss, Inc.
Who reads Expression in lung tumors and genetic mapping of the novel murine protein kinase Cη?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Federico Canzian; Manuela Gariboldi; Giacomo Manenti; Laura De Gregorio; Shin‐Ichi Osada; Shigeo Ohno; Tommaso A. Dragani; Marco A. Pierotti
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0899-1987)
- Published
- 1994
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)