Can I read Field Carcinogenesis for Risk Stratification of Colorectal Cancer on EtoBox?

Field Carcinogenesis for Risk Stratification of Colorectal Cancer by Dionne Rebello; Elliott Rebello; Matthew Custodio; Xixi Xu; Sanil Gandhi; Hemant K. Roy is a book available to read on EtoBox.

What is Field Carcinogenesis for Risk Stratification of Colorectal Cancer about?

Colorectal cancer (CRC) is characterized by genetic-environmental interplay leading to diffuse changes in the entire colonic mucosa (field carcinogenesis or field of injury) and to a pro-neoplastic genetic/epigenetic/physiological milieu. The clinical consequences are increased risk of synchronous and metachronous neoplasia. Factors such as genetics, race, ethnicity, age, and socioeconomic status are thought to influence neoplasia development. Here, we explore the potential improvement to CRC screening through exploiting field carcinogenesis, with particular focus on racial disparities and chemoprevention strategies. Also, we discuss future directions for field carcinogenesis/risk stratification using molecular and novel biophotonic techniques for personalized CRC screening.

Author

Dionne Rebello; Elliott Rebello; Matthew Custodio; Xixi Xu; Sanil Gandhi; Hemant K. Roy

Publisher

Elsevier Science & Technology

Published

2021

Language

EN

ISBN

9780128240786

Subjects

Medical, Science, Biology