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The study focuses on formulating a Letrozole nanosuspension using the probe sonication method and Box-Behnken design to enhance its solubility and bioavailability. The optimized formulation, NS4, demonstrated a significant increase in solubility up to 90% compared to pure Letrozole, with favorable characteristics such as a particle size of 923.5nm and 94.02% drug release within 2 hours. This research highlights the potential of nanosuspension technology in improving the therapeutic efficacy of Letrozole for

Author

kompalli Krishna

Language

EN