Can I read A Connectome-Wide Functional Signature of Trait Anger on EtoBox?

A Connectome-Wide Functional Signature of Trait Anger by M. Justin Kim; Maxwell L. Elliott; Annchen R. Knodt; Ahmad R. Hariri is a Psychology article available to read on EtoBox.

What is A Connectome-Wide Functional Signature of Trait Anger about?

Past research on the brain correlates of trait anger has been limited by small sample sizes, a focus on relatively few regions of interest, and poor test–retest reliability of functional brain measures. To address these limitations, we conducted a data-driven analysis of variability in connectome-wide functional connectivity in a sample of 1,048 young adult volunteers. Multidimensional matrix regression analysis showed that self-reported trait anger maps onto variability in the whole-brain functional connectivity patterns of three brain regions that serve action-related functions: bilateral supplementary motor areas and the right lateral frontal pole. We then demonstrate that trait anger modulates the functional connectivity of these regions with canonical brain networks supporting somatomotor, affective, self-referential, and visual information processes. Our findings offer novel neuroimaging evidence for interpreting trait anger as a greater propensity to provoked action, which supports ongoing efforts to understand its utility as a potential transdiagnostic marker for disordered states characterized by aggressive behavior.

Who reads A Connectome-Wide Functional Signature of Trait Anger?

Author

M. Justin Kim; Maxwell L. Elliott; Annchen R. Knodt; Ahmad R. Hariri

Publisher

SAGE Publications

Published

2021

Language

EN

Field

Psychology (Social Sciences)