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Biomimetic Organic–inorganic Nanocomposite Coatings for Titanium Implants by Maja Dutour Sikirić; Csilla Gergely; Rene Elkaim; Ellen Wachtel; Frederic J. G. Cuisinier; Helga Füredi-Milhofer is a Engineering article available to read on EtoBox.

What is Biomimetic Organic–inorganic Nanocomposite Coatings for Titanium Implants about?

## Abstract A new class of organic–inorganic nanocomposites, to be used as coatings for surface enhancement of metal implants for bone replacement and repair, has been prepared by a biomimetic three‐step procedure: (1) embedding amorphous calcium phosphate (ACP) particles between organic polyelectrolyte multilayers (PE MLs), (2) __in situ__ transformation of ACP to octacalcium phospate (OCP) and/or poorly crystalline apatite nanocrystals by immersion of the material into a metastable calcifying solution (MCS) and (3) deposition of a final PE ML. The organic polyelectrolytes used were poly‐L‐glutamic acid and poly‐L‐lysine. The nanocomposites obtained by each successive step were characterized by scanning electron microscopy, energy dispersive X‐ray analysis (EDS), and XRD, and their suitability as coatings for metal implants was examined by mechanical and __in vitro__ biological tests. Coatings obtained by the first deposition step are mechanically unstable and therefore not suitable. During the second step, upon immersion into MCS, ACP particles were transformed into crystalline calcium phosphate, with large platelike OCP crystals as the top layer. After phase transformation, the

Who reads Biomimetic Organic–inorganic Nanocomposite Coatings for Titanium Implants?

Author

Maja Dutour Sikirić; Csilla Gergely; Rene Elkaim; Ellen Wachtel; Frederic J. G. Cuisinier; Helga Füredi-Milhofer

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1549-3296)

Published

2008

Language

EN

Field

Engineering (Physical Sciences)