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Can I read Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis on EtoBox?
Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis by Srinivasan Mani; Snehashis Hazra; Joseph Hagan; Amy Sisson; Jayasree Nair; Mohan Pammi is a Medicine article available to read on EtoBox.
What is Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis about?
## CONTEXT Necrotizing enterocolitis (NEC) is a devastating intestinal disease affecting preterm infants. Studies implicate viral infections in etiopathogenesis. ## OBJECTIVE To summarize the association of viral infections with NEC by systematic review and meta-analysis. ## DATA SOURCES We searched Ovid-Medline, Embase, Web of Science, and Cochrane databases in November 2022. ## STUDY SELECTION We included observational studies that examined the association between viral infections and NEC in newborn infants. ## DATA EXTRACTION We extracted data regarding the methodology, participant characteristics, and outcome measures. ## RESULTS We included 29 and 24 studies in the qualitative review and meta-analysis, respectively. The meta-analysis demonstrated a significant association between viral infections and NEC (odds ratio [OR], 3.81, 95% confidence interval: 1.99–7.30, 24 studies). The association remained significant after excluding the outliers (OR, 2.89 [1.56–5.36], 22 studies) and studies with poor methodology (OR, 3.33 [1.73–6.43], 22 studies). In subgroup analysis based on participants' birth weight, studies including very low birth weight infants only (OR, 3.62 [1.63–8.03], 8
Who reads Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Srinivasan Mani; Snehashis Hazra; Joseph Hagan; Amy Sisson; Jayasree Nair; Mohan Pammi
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)