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Biocompatibility of a New Radiopaque Iodine‐containing Acrylic Bone Cement by Catharina S. J. van Hooy‐Corstjens; Sjoerd K. Bulstra; Menno L. W. Knetsch; Piet Geusens; Roel Kuijer; Leo H. Koole is a Medicine article available to read on EtoBox.

What is Biocompatibility of a New Radiopaque Iodine‐containing Acrylic Bone Cement about?

## Abstract Radiopacity in the vast majority of the commercially available acrylic bone cements that are used clinically is provided by particles of either BaSO~4~ or ZrO~2~. Literature reports have shown these agents to have a detrimental effect on some mechanical properties of the cements as well as on its biological response. We, therefore, have developed a new type of bone cement, for which radiopacity results from the presence of an iodine‐containing methacrylic copolymer. The focus of the present work was the comparison of the biocompatibility of this new cement and a commercially available cement that contains barium sulfate. __In vitro__ experiments show that both cements are cytocompatible materials, for which no toxic leachables are found. Implantation of the cements in a rabbit for three months resulted in the occasional presence of a thin fibrous tissue at the cement–bone interface, which is common for acrylic bone cements. Consideration of all the results led to the conclusion that the new cement is as biocompatible as the BaSO~4~‐containing one. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2007

Who reads Biocompatibility of a New Radiopaque Iodine‐containing Acrylic Bone Cement?

Author

Catharina S. J. van Hooy‐Corstjens; Sjoerd K. Bulstra; Menno L. W. Knetsch; Piet Geusens; Roel Kuijer; Leo H. Koole

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1552-4973)

Published

2006

Language

EN

Field

Medicine (Health Sciences)