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Evaluation of Esmolol for Heart Rate Control in Patients with Acute Aortic Dissection by Krenz, J.R.; O'Brien, M.E.; Lee, J.; Hayes, B.D. is a Medicine article available to read on EtoBox.

What is Evaluation of Esmolol for Heart Rate Control in Patients with Acute Aortic Dissection about?

## Purpose: Acute aortic dissection is a serious and life-threatening condition that requires prompt, effective management. the purpose of this study was to evaluate the efficacy and safety of esmolol for heart rate control in patients with acute aortic dissection in the emergency department (ed). ## Methods: This was a retrospective, descriptive analysis of patients treated for type a or type b acute aortic dissection in the ed at an academic medical center. the primary outcome was the proportion of patients achieving strict (≤60 bpm) or lenient (≤80 bpm) heart rate control within the first 60 min of therapy at the study site. the primary safety endpoint was the incidence of hypotension, defined as a systolic blood pressure of <90 mmhg or a mean arterial pressure of ≤60 mmhg. ## Results: Of 266 patients screened, 40 patients met inclusion criteria. thirty-three patients (82.5%) attained lenient rate control within the first 60 min of esmolol therapy. eleven patients (27.5%) achieved a strict heart rate goal within the first 60 min of esmolol therapy. five patients (12.5%) experienced an episode of hypotension during the first 3 h of esmolol therapy. ## Conclusion: In patients trea

Who reads Evaluation of Esmolol for Heart Rate Control in Patients with Acute Aortic Dissection?

Author

Krenz, J.R.; O'Brien, M.E.; Lee, J.; Hayes, B.D.

Publisher

Elsevier Science; Elsevier ; W. B. Saunders Co., Ltd.; Elsevier BV (ISSN 1532-8171)

Published

2020

Language

EN

Field

Medicine (Health Sciences)