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1) Passive immunization (PI) using broadly neutralizing antibodies (bnAbs) can achieve a functional cure for HIV by increasing the neutralizing activity of endogenously generated antibodies even after the administered antibodies have waned. 2) PI affects the germinal center reaction by increasing the selection stringency on B cells to acquire antigen from follicular dendritic cells. Intermediate affinity PI provides the optimal quality-quantity tradeoff. 3) Both the antiviral effect from rapid antigen c

Author

SOUMYA MITTAL

Language

EN