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Peroperative Treatment with I.v. Ketoprofen Reduces Pain and Vomiting in Children After Strabismus Surgery by H. Kokki; E. Homan; K. Tuovinen; S. Purhonen is a Medicine article available to read on EtoBox.

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Background: Strabismus surgery is associated with both pain and vomiting. Ketoprofen is widely used in adults to treat acute pain, but there are only few reports of its use in children. This randomised, double‐blind, placebo‐controlled, parallel group study was designed to investigate the analgesic effect of i.v. ketoprofen and its effect on the incidence of vomiting in children after day‐case strabismus surgery. Methods: Fifty‐nine ASA 1 children, aged 1–12 years, entered the study. After premedication with diazepam and glycopyrronium, anaesthesia was induced with fentanyl and propofol and maintained with isoflurane. After induction the children in the ketoprofen group received 1 mg kg^−1^ ketoprofen followed by an infusion of 1 mg kg^−1^ ketoprofen over 2 h. In the placebo group, children received 0.9% saline. The postoperative pain was assessed by the Maunuksela pain score (0=no pain, 10=worst possible pain). All children received fentanyl as a rescue analgesic if the Maunuksela score was ≥3. Results: In the ketoprofen group the number of fentanyl doses was smaller compared to the placebo group (median 1, quartiles (0–2) vs. 2 (1–3), __P__=0.047). The children in the ketoprofen

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Author

H. Kokki; E. Homan; K. Tuovinen; S. Purhonen

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0001-5172)

Published

1999

Language

EN

Field

Medicine (Health Sciences)