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Do Traditional Symptoms of Hypothyroidism Correlate with Biochemical Disease? by Gay J. Canaris; John F. Steiner; E. Chester Ridgway is a Medicine article available to read on EtoBox.

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## Objective: Hypothyroidism often remains undetected because of the difficulty associating symptoms with disease. to determine the relation between symptoms and biochemical disease, we assessed symptoms and serum thyroid function tests, concurrently, for patients with and without hypothyroidism. ## Design: Cross-sectional study. ## Setting/patients: Seventy-six newly diagnosed case patients with overt hypothyroidism and 147 matched control patients identified through outpatient laboratories in michigan and colorado. ## Measurements and main results: Patient symptoms were assessed by questionnaire. case patients reported a higher proportion of hypothyroid symptoms than did control patients (30.2% vs 16.5%, p < .0001). univariate analysis identified three significant predictors of an elevated level of thyroid-stimulating hormone (tsh) (p < .05), and 13 symptoms which, when they had changed in the past year, were reported more often by case patients with hypothyroidism than by control patients (p < .005). individuals reporting changes in 7 or more symptoms were significantly more likely to have hypothyroidism (likelihood ratio [lr] = 8.7, 95% confidence interval [ci] 3.8, 20.2); thos

Who reads Do Traditional Symptoms of Hypothyroidism Correlate with Biochemical Disease??

Author

Gay J. Canaris; John F. Steiner; E. Chester Ridgway

Publisher

John Wiley and Sons; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0884-8734)

Published

1997

Language

EN

Field

Medicine (Health Sciences)