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Technical Data: M.Wt: 136.15 Formula: C7H8N2O Solubility: DMSO Purity: >99% Storage: at -20℃ 2 years CAS No.: 3544-24-9 Biological Activity of INO-1001: INO-1001 is an isoindolinone derivative and potent inhibitor of the nuclear enzyme PARP (poly (ADP-ribose) polymerase) with chemosensitization and radiosensitization properties[1,2]. INO-1001 inhibits PARP, which may result in inhibition of tumor cell DNA repair mechanisms and, so, tumor cell resistance to chemotherapy and radiation therapy. PARP enzymes a

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Selleck Chem

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