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What is DMARDs in Rheumatology: MMF, Azathioprine, Tacrolimus about?

Mycophenolate mofetil (MMF), azathioprine, and tacrolimus are conventional DMARDs originally developed for transplantation that have been repurposed for rheumatic diseases. These drugs inhibit cell proliferation through various mechanisms, with MMF and azathioprine targeting the purine pathway and tacrolimus inhibiting lymphocyte activation. Ongoing research is exploring their effectiveness in treating conditions such as lupus nephritis, interstitial lung disease, and skin fibrosis, as well as optimizing do

Author

firephoenix754

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EN