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Combining Ic50 or Ki Values From Different Sources Is A Source of Significant Noise by mbryden is a document available to read on EtoBox.
The article discusses the significant noise introduced when combining IC50 and Ki values from different assays, emphasizing the scientific risks of merging incompatible data. It highlights that nearly 65% of combined IC50 data points differ by more than 0.3 log units, suggesting the need for careful curation to improve data quality for machine learning models in bioactivity prediction. The authors propose a
- Author
- mbryden
- Language
- EN