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What is Proliposome Development for Lopinavir Bioavailability about?

This study focuses on the development of proliposomes for the poorly soluble drug lopinavir (LPV) using Quality by Design (QbD) principles to enhance oral bioavailability. The research identified critical quality attributes and optimized formulation parameters, resulting in proliposomes with over 90% entrapment efficiency and significant improvements in bioavailability compared to existing formulations. Stability studies confirmed the optimized proliposome

Author

alexanderaristizabal

Language

EN