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What is Dextromethorphan Effects on Rat Liver Histopathology about?
This document summarizes a study on the effect of different doses of dextromethorphan administered orally on the histopathology of the livers of Wistar rats. 24 male Wistar rats were divided randomly into 4 groups: a control group and 3 treatment groups receiving doses of 0.175 mg/gBW, 0.35 mg/gBW, and 0.7mg/gBW of dextromethorphan respectively. Liver samples were analyzed and the degree of hepatocyte destruction was measured. The highest liver histopathology score was found in the 0.35 mg/gBW group. Statis
- Author
- Putri Rachmawati
- Language
- EN