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Evolution in Technique for Vestibular Schwannoma Radiosurgery and Effect on Outcome by John C. Flickinger; Douglas Kondziolka; Bruce E. Pollock; L.Dade Lunsford is a Medicine article available to read on EtoBox.

What is Evolution in Technique for Vestibular Schwannoma Radiosurgery and Effect on Outcome about?

Purpose: To define changes in treatment technique for vestibular scbwannoma radiosurgery and to relate them wges in outcome, a large single institution experience was reviewed. Methods and Materials: Two hundred seventy-three patients with unilateral vestibulsr scbwaunoasasu~derwent Gamma knife radiosurgery: 118 with computed tomography (CT) treatment planning during 1987-1991, and 155 with magnetic resonance imaging (MR) treatment planning in 1991-1994. Mean treatment fered between tbe CT and MR groups: minimum tumor dose @,,& was 17 vs. 14 Gy, number o 3.4 vs. 5.8, and volume was 3.5 vs. 2.7 cc., respectively. Results: The actuarial 7-year clinical tumor control rate (no requirement for surgical b&ervention) for the entire series was 96.4 t 2.3%, with a radiographic tumor control rate of 91.0 ? 3.4% CT and MR groups. Significantly lower rates of postradiosurgery facial, trige were observed in the MR group compared to the CT group. Multivariate analyses correlations of increasing rates of facial and trigemlnal neuropatby with increasing transverse tusng'r diameter and J-b, as well as with CT treatment planning (compared to MR). Decreased hearing was si~larly correlated with diamet

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Author

John C. Flickinger; Douglas Kondziolka; Bruce E. Pollock; L.Dade Lunsford

Publisher

Elsevier BV

Published

1996

Language

EN

Field

Medicine (Health Sciences)