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Lessons learned from patient outcomes when lowering hemoglobin transfusion thresholds during COVID-19 blood shortages by Jesse Qiao; Bradford Ray; Vishwajeet Singh; Aaron Geno; Jude Abadie is a Medicine article available to read on EtoBox.

What is Lessons learned from patient outcomes when lowering hemoglobin transfusion thresholds during COVID-19 blood shortages about?

Abstract Objectives This study examines whether patient outcomes were affected when the hemoglobin (Hb) transfusion threshold was lowered by 1 g/dL during COVID-19–related blood shortages. Methods Outcomes of lowered Hb thresholds (from <7 to <6 g/dL) were defined by 14-month intervals in 2 patient groups (prepandemic [January 2019-February 2020] and pandemic [April 2020-May 2021]). We evaluated patient admissions, pretransfusion (if transfused) or nadir admission (if not transfused) Hb levels between 5.0 and 8.0 g/dL, and total red blood cell (RBC) transfusions during admission (if transfused). Baseline variables and outcomes were selected from electronic health records. Primary COVID-19–related admissions were excluded. Regression analysis was conducted to determine outcomes. Results Those in the prepandemic group (1976) and pandemic group (1547) were transfused. Fewer RBCs (2186, vs 3337) were used in the prepandemic group than in the pandemic group, respectively. Those in the prepandemic group had significantly higher rates of hypertension and diabetes as well as more smokers. Significant differences were observed when comparing the number of procedures and incidence of sepsis

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Author

Jesse Qiao; Bradford Ray; Vishwajeet Singh; Aaron Geno; Jude Abadie

Publisher

Oxford University Press (OUP)

Published

2023

Language

EN

Field

Medicine (Health Sciences)