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Regulated Proteolysis in Microorganisms Volume 66 by Dougan, David A. is a scholarly article available to read on EtoBox.

What is Regulated Proteolysis in Microorganisms Volume 66 about?

This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker's yeast Saccharomyces cerevisiae). For many years, intracellular protein degradation was almost exclusively thought of as a non-selective mechanism to recycle amino acids and remove trash from the cell. The contemporary view however, is that protein degradation is a highly selective process that plays a key role in a number of important cellular processes. Not only does it contribute to the maintenance of protein homeostasis (proteostasis) through the direct recognition and removal of damaged proteins, but it also regulates the cells response to a variety of environmental stress signals. Regulatory proteolysis also plays an important role in virulence of pathogenic bacteria, and "fitness" of eukaryotic organelles. This book focuses on the central players in these diverse cellular processes - the AAA+ proteases - and examines how these machines achieve their exquisite specificity. It also hi

Author

Dougan, David A.

Publisher

Springer Netherlands : Imprint: Springer

Published

2013

Language

EN

ISBN

9789400759404