Opening book details…
Can I read Analysis of the potential impact of durability, timing, and transmission blocking of COVID-19 vaccine on morbidity and mortality on EtoBox?
Analysis of the potential impact of durability, timing, and transmission blocking of COVID-19 vaccine on morbidity and mortality by Haghpanah, Fardad (author);Lin, Gary (author);Levin, Simon A. (author);Klein, Eili (author) is a Medicine article available to read on EtoBox.
What is Analysis of the potential impact of durability, timing, and transmission blocking of COVID-19 vaccine on morbidity and mortality about?
## Background COVID-19 vaccines have been approved and made available. While questions of vaccine allocation strategies have received significant attention, important questions remain regarding the potential impact of the vaccine given uncertainties regarding efficacy against transmission, availability, timing, and durability. ## Methods We adapted a susceptible-exposed-infectious-recovered (SEIR) model to examine the potential impact on hospitalization and mortality assuming increasing rates of vaccine efficacy, coverage, and administration. We also evaluated the uncertainty of the vaccine to prevent infectiousness as well as the impact on outcomes based on the timing of distribution and the potential effects of waning immunity. ## Findings Increased vaccine efficacy against disease reduces hospitalizations and deaths from COVID-19; however, the relative benefit of transmission blocking varied depending on the timing of vaccine distribution. Early in an outbreak, a vaccine that reduces transmission will be relatively more effective than one introduced later in the outbreak. In addition, earlier and accelerated implementation of a less effective vaccine is more impactful than later
Who reads Analysis of the potential impact of durability, timing, and transmission blocking of COVID-19 vaccine on morbidity and mortality?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Haghpanah, Fardad (author);Lin, Gary (author);Levin, Simon A. (author);Klein, Eili (author)
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)