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Movement Disorders: Role of Imaging in Diagnosis by Mario Mascalchi; Alessandra Vella; Roberto Ceravolo is a Medicine article available to read on EtoBox.

What is Movement Disorders: Role of Imaging in Diagnosis about?

## Abstract Magnetic resonance imaging (MRI and single‐photon emission computed tomography (SPECT) have a considerable role in the diagnosis of the single patient with movement disorders. Conventional MRI demonstrates symptomatic causes of parkinsonism but does not show any specific finding in Parkinson's disease (PD). However, SPECT using tracers of the dopamine transporter (DAT) demonstrates an asymmetric decrease of the uptake in the putamen and caudate from the earliest clinical stages. In other degenerative forms of parkinsonism, including progressive supranuclear palsy (PSP), multisystem atrophy (MSA), and corticobasal degeneration (CBD), MRI reveals characteristic patterns of regional atrophy combined with signal changes or microstructural changes in the basal ganglia, pons, middle and superior cerebellar peduncles, and cerebral subcortical white matter. SPECT demonstrates a decreased uptake of tracers of the dopamine D2 receptors in the striata of patients with PSP and MSA, which is not observed in early PD. MRI also significantly contributes to the diagnosis of some inherited hyperkinetic conditions including neurodegeneration with brain iron accumulation and fragile‐X tre

Who reads Movement Disorders: Role of Imaging in Diagnosis?

Author

Mario Mascalchi; Alessandra Vella; Roberto Ceravolo

Publisher

Wiley

Published

2012

Language

EN

Field

Medicine (Health Sciences)